Activating Compound | Comment | Organism | Structure |
---|---|---|---|
alpha-lactalbumin | stimulates transfer of galactose from UDPgalactose to N-acetylgalactosamine | Homo sapiens |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
alpha1-Acid glycoprotein | above 1.4 mM with respect to acceptor sites | Homo sapiens | |
N-acetylglucosamine | above 10 mM | Homo sapiens |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.0039 | - |
N-acetylglucosamine | - |
Homo sapiens | |
0.024 | - |
UDPgalactose | - |
Homo sapiens | |
0.2 | - |
alpha1-Acid glycoprotein | - |
Homo sapiens |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
soluble | - |
Homo sapiens | - |
- |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Mn2+ | required | Homo sapiens | |
Mn2+ | Km: 0.4 mM | Homo sapiens |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
85000 | 90000 | gel filtration | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Purification (Comment) | Organism |
---|---|
- |
Homo sapiens |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
plasma | - |
Homo sapiens | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
0.535 | - |
- |
Homo sapiens |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
UDPgalactose + alpha1-acid glycoprotein | - |
Homo sapiens | ? | - |
? | |
UDPgalactose + degalactosylated fetuin | - |
Homo sapiens | UDP + fetuin containing beta-1,4-galactose linkages | - |
? | |
UDPgalactose + glucose | in presence of alpha-lactalbumin | Homo sapiens | lactose + UDP | - |
? |
Subunits | Comment | Organism |
---|---|---|
? | x * 70000-80000, SDS-PAGE | Homo sapiens |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
30 | - |
reaction with N-acetylglucosamine and UDPgalactose, reaction with alpha1-acid glycoprotein and UDPgalactose | Homo sapiens |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
7.5 | - |
reaction with N-acetylglucosamine and UDPgalactose, reaction with alpha1-acid glycoprotein and UDPgalactose | Homo sapiens |